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NuPhedrine is one of the more recent diet pills making waves in the weight loss industry. It has many audacious claims, such as letting users burn calories more quickly and increasing stamina. NuPhedrine uses its ingredients to carry its name — South African Hoodia, Slimaluma, and Advantra-Z. The diet pill’s makers also insist that it does not cause any side effects. If you visit their Web site, you’ll find a lot of “before and after” photos of supposedly satisfied customers, although you can’t really be sure if they’re the same people. So with any other diet pill that makes a splash in the market, it’s important to know as much as you can about NuPhedrine before you actually go out and buy it.

Hoodia Gordonii

This plant grows in Namibia and South Africa, and has a bitter taste that helped bushmen hunters survive long hunting trips by suppressing the appetite. The hoodia’s hunger suppression element, p57, can be isolated from the plant, but no tests have proven any real capability to suppress the appetite. While the manufacturers of NuPhedrine have certification that the diet pill does contain South African hoodia, independent clinical tests haven’t been made to prove this claim yet. In addition, we can’t really tell whether the p57 amounts in NuPhedrine are actually high enough to affect hunger.

It also hasn’t been verified whether or not hoodia causes side effects. Pfizer, the worldwide pharmaceutical heavyweight, once had the license to develop the plant, but relinquished the rights after realizing it wasn’t easy to do so. It was also suspected that hoodia may be bad for the liver. Since only bushmen have used hoodia to any good extent, it’s still unclear whether it’s really safe for humans. To be on the safe side, stay away from hoodia if you have any kidney or liver problems, if you’re pregnant or nursing, or if you’re under the age of 18. Likewise, avoid hoodia if you have diabetes — it can cause your blood sugar levels to drop.

Advantra-Z

This is synephrine’s, or bitter orange’s, patented version — it has vitamins and some protein thrown into the mix. Bitter orange is a stimulant like ephedrine, and also makes you feel less hungry. Bitter orange has taken the place of ephredine in the diet supplement scene after the latter got banned. NuPhedrine manufacturers insist that Advantra-Z doesn’t have caffeine or ephedra, but bitter orange still has the same side effects, such as spiking the blood pressure.

Slimaluma

Slimaluma is a more standard form of another cactus-like plant, India’s caralluma fimbriata. Like hoodia, it’s been used to suppress hunger by Indians for hundreds of years. Some small scientific studies have been made on slimaluma and has confirmed the plant’s tendency to suppress hunger and burn fat. More substantial studies have to be done, though, both to support caralluma fimbriata’s weight loss benefits and find out whether it really is free of side effects.